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Hyaluronic acid vs CaHA vs PCL fillers
Hyaluronic acid fillers add volume and can be dissolved; calcium hydroxylapatite and polycaprolactone fillers stimulate collagen and last longer but cannot be dissolved. HArmonyCa combines both approaches.
Updated 9 October 2026
| Product | Material | Main effect | Reversible | Duration (manufacturer-stated, approx.) |
|---|---|---|---|---|
| Juvéderm | Hyaluronic acid | Volume and hydration | Yes, with hyaluronidase | About 9–24 months depending on line |
| Radiesse | Calcium hydroxylapatite (CaHA) | Volume plus collagen stimulation | No | About 12–18 months |
| HArmonyCa | Hyaluronic acid + CaHA | Lift plus collagen stimulation | HA part only | About 12 months |
| Ellansé | Polycaprolactone (PCL) | Collagen stimulation | No | S about 1 year, M about 2 years |
Durations are approximate figures from manufacturer materials and vary by patient, area and technique.
Which to stock
- Juvéderm: the core range for most clinics; reversible, with a line for each treatment area.
- Radiesse and Ellansé: for clinics offering longer-lasting contouring and skin-quality treatments.
- HArmonyCa: for lower-face lift with collagen stimulation in one product.